Richard A. Wilson's Research
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PH.D., Imperial College London, 1998
Dr. Wilson is interested in asking the question: How does a plant pathogenic fungus perceive its environment and cause disease? To answer this, his research is directed towards understanding the genetic and biochemical networks that underlie the molecular interactions between fungi and plant host. His approach uses molecular genetics and biochemical analysis, coupled with high-throughput post-genomic technologies, to identify and characterize the gene expression networks, protein interactions, biochemical processes, signaling pathways and effector molecules that mediate the plant-fungal interaction. Focusing on economically important pathogens such as the devastating rice blast fungus M. oryzae and the mycotoxigenic fungi, such an approach would ultimately identify novel determinants of virulence that could be exploited as drug targets in the fight against these recalcitrant pathogens.